Anti-HLA-C Polyclonal Antibody
产品名称: Anti-HLA-C Polyclonal Antibody
英文名称: Anti-HLA-C Polyclonal Antibody
产品编号: K001854P
产品价格: null
产品产地: 北京
品牌商标: Solarbio
更新时间: 2025-11-13T16:50:54
使用范围:
北京索莱宝科技有限公司
- 联系人 : 索莱宝-龚思雨
- 地址 : 北京市北京经济技术开发区环科中路16号26幢3层301
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- 所在区域 : 北京
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Anti-HLA-C Polyclonal Antibody
Anti-HLA-C Polyclonal Antibody
品牌:solarbio | 货号:K001854P
| 英文名称 | Anti-HLA-C Polyclonal Antibody |
|---|---|
| 别名 | D6S204;HLA-JY3;HLAC;HLC-C;MHC;PSORS1 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 41kDa |
| Gene ID | 3107 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human HLA-C |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human HLA-C |
| Subcellular Locations | Membrane Single-pass type I membrane protein |
| Swiss Prot | P10321 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | HLA-C belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Over one hundred HLA-C alleles have been described |
